| Gene Information | |
|---|---|
| Gene Name | SEC24D |
| Organism | Homo sapiens (Human) |
| Gene Length | 1032 |
| Protein Names | Protein transport protein Sec24D (SEC24-related protein D) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000150961 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O94855 |
| Gene Card | SEC24D |
| Uniprot ID | O94855 |
| Pfam | PF00626; PF08033; PF04815; PF04811; PF04810 |
| In ASD | no |
| Allosteric Prediction | no (-0.130521395) |
| Ortholog in Animals | Alpaca_ SEC24D ( ortholog_one2one ) Dog_ SEC24D ( ortholog_one2one ) GuineaPig_ SEC24D ( ortholog_one2one ) Macaque_ SEC24D ( ortholog_one2one ) Mouse_ Sec24d ( ortholog_one2one ) Pig_ SEC24D ( ortholog_one2one ) Rat_ Sec24d ( ortholog_one2one ) Rabbit_ SEC24D ( ortholog_one2one ) |
| Ohnologs | SEC24C |
| Paralogs | SEC24A, SEC24B |
| Tissue | testis |
| Tissue Specificity | Ubiquitously expressed, with higher amounts in placenta, pancreas, heart and liver. {ECO:0000269|PubMed:10329445}. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.025393(Mouse);0.002490(Rat);0.067069(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3EFO (X-ray 2.70A ) 3EG9 (X-ray 3.00A ) 5KYU (X-ray 3.51A ) 5KYW (X-ray 3.20A ) 5KYX (X-ray 3.52A ) 5KYY (X-ray 3.40A ) |
| DBSNP | rs10029206 rs6844109 rs11723368 rs786204846 rs760670617 |
| Subcellular location [CC] | Cytoplasmic vesicle, COPII-coated vesicle membrane {ECO:0000269|PubMed:10329445}; Peripheral membrane protein {ECO:0000250|UniProtKB:P53992}; Cytoplasmic side {ECO:0000250|UniProtKB:P53992}. Endoplasmic reticulum membrane {ECO:0000305|PubMed:10329445}; Peripheral membrane protein {ECO:0000250|UniProtKB:P53992}; Cytoplasmic side {ECO:0000250|UniProtKB:P53992}. Cytoplasm, cytosol {ECO:0000250|UniProtKB:P53992}. |
| Mouse PG classification | LPG |
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