| Gene Information | |
|---|---|
| Gene Name | SLC32A1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 525 |
| Protein Names | Vesicular inhibitory amino acid transporter (GABA and glycine transporter) (Solute carrier family 32 member 1) (Vesicular GABA transporter) (hVIAAT) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000101438 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9H598 |
| Gene Card | SLC32A1 |
| Uniprot ID | Q9H598 |
| Pfam | PF01490 |
| In ASD | no |
| Allosteric Prediction | yes (0.135165286) |
| Ortholog in Animals | Alpaca_ SLC32A1 ( ortholog_one2one ) Dog_ SLC32A1 ( ortholog_one2one ) GuineaPig_ SLC32A1 ( ortholog_one2one ) Macaque_ SLC32A1 ( ortholog_one2one ) Mouse_ Slc32a1 ( ortholog_one2one ) Pig_ SLC32A1 ( ortholog_one2one ) Rat_ Slc32a1 ( ortholog_one2one ) Rabbit_ SLC32A1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SLC38A3, SLC36A1, SLC36A4, SLC38A10, SLC38A9, SLC36A3, SLC38A7, SLC38A8, SLC38A2, SLC36A2, SLC38A4, SLC38A11, SLC38A6, SLC38A1, SLC38A5 |
| Tissue | brain, caudate.nucleus, diencephalon, putamen, nucleus.accumbens |
| Tissue Specificity | Retina. Expressed throughout the horizontal cells or more specifically at the terminals. {ECO:0000269|PubMed:12115694}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34517228 |
| Subcellular location [CC] | Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:O35458}; Multi-pass membrane protein {ECO:0000255}. Presynapse {ECO:0000250|UniProtKB:O35633}. Note=Presents in glycine-, GABA- or GABA- and glycine-containing boutons. {ECO:0000250|UniProtKB:O35458}. |
| Mouse PG classification | NA |
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