| Gene Information | |
|---|---|
| Gene Name | SAB |
| Organism | Homo sapiens (Human) |
| Gene Length | 455 |
| Protein Names | SH3 domain-binding protein 5 (SH3BP-5) (SH3 domain-binding protein that preferentially associates with BTK) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O60239 |
| Gene Card | SH3BP5 |
| Uniprot ID | O60239 |
| Pfam | PF05276 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in testis and ovaries. It is also expressed in a variety of tissues including spleen, lymph node, thymus, bone marrow, fetal liver, colon, small intestine and prostate. {ECO:0000269|PubMed:9571151}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.1(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4H3B (X-ray 2.08A ) 6DJL (X-ray 3.10A ) 6IXE (X-ray 3.35A ) 6IXF (X-ray 3.60A ) 6IXG (X-ray 3.80A ) 6IXV (X-ray 3.80A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasmic vesicle membrane {ECO:0000269|PubMed:30217979}; Peripheral membrane protein {ECO:0000269|PubMed:30217979}. Mitochondrion {ECO:0000269|PubMed:12167088}. Note=Colocalizes with RAB11A on cytoplasmic vesicle membranes. {ECO:0000269|PubMed:30217979}. |
| Mouse PG classification | NA |
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