| Gene Information | |
|---|---|
| Gene Name | GPR68 |
| Organism | Homo sapiens (Human) |
| Gene Length | 365 |
| Protein Names | Ovarian cancer G-protein coupled receptor 1 (OGR-1) (G-protein coupled receptor 68) (GPR12A) (Sphingosylphosphorylcholine receptor) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000119714 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q15743 |
| Gene Card | GPR68 |
| Uniprot ID | Q15743 |
| Pfam | PF00001 |
| In ASD | yes |
| Allosteric Prediction | yes (0.999670823) |
| Ortholog in Animals | Alpaca_ GPR68 ( ortholog_one2one ) Dog_ GPR68 ( ortholog_one2one ) GuineaPig_ GPR68 ( ortholog_one2one ) Macaque_ GPR68 ( ortholog_one2one ) Mouse_ Gpr68 ( ortholog_one2one ) Pig_ GPR68 ( ortholog_one2one ) Rat_ Gpr68 ( ortholog_one2one ) Rabbit_ GPR68 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | LPAR5 |
| Tissue | NA |
| Tissue Specificity | Found at low level in a wide range of tissues, but significantly expressed in lung, kidney, bone and nervous system. {ECO:0000269|PubMed:12955148}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2230339 rs1057517672 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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