| Gene Information | |
|---|---|
| Gene Name | RAB13 |
| Organism | Homo sapiens (Human) |
| Gene Length | 203 |
| Protein Names | Ras-related protein Rab-13 (Cell growth-inhibiting gene 4 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000143545 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P51153 |
| Gene Card | RAB13 |
| Uniprot ID | P51153 |
| Pfam | PF00071 |
| In ASD | no |
| Allosteric Prediction | no (-0.749061367) |
| Ortholog in Animals | Alpaca_ RAB13 ( ortholog_one2one ) Dog_ RAB13 ( ortholog_one2many ) GuineaPig_ RAB13 ( ortholog_one2one ) Macaque_ RAB13 ( ortholog_one2one ) Mouse_ Rab13 ( ortholog_one2one ) Pig_ RAB13 ( ortholog_one2one ) Rat_ Rab13 ( ortholog_one2one ) Rabbit_ RAB13 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RAB14, RAB5C, RAB39A, RAB27B, RAB36, RAB33B, RABL2A, RABL2B, RAB27A, RAB3C, RAB5A, RAB15, RAB40AL, RAB3A, RAB40C, RAB12, RAB8A, RAB17, RAB20, RAB24, RAB44, RAB1A, RAB11A, RAB31, RAB7A, IFT27, RAB29, RAB33A, RAB9B, RAB10, RAB4B, RAB32, RAB4A, RAB19, RAB42, RAB9A, RAB40A, RAB11B, RAB2B, RAB2A, RAB43, RAB18, RAB37, RAB25, RASEF, RAB6D, RAB6C, RAB8B, RAB41, RAB40B, RAB21, RAB39B, RAB28, RAB5B, RAB38, RAB3B, RAB34, RAB7B, RAB35, RAB3D, RAB1B, RAB6B, RAB22A, RAB26, RAB23, RAB30, RAB6A, DNAJC27 |
| Tissue | NA |
| Tissue Specificity | Detected in several types of epithelia, including intestine, kidney, liver and in endothelial cells. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001293(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:15528189}; Lipid-anchor {ECO:0000305|PubMed:8375503}; Cytoplasmic side {ECO:0000305|PubMed:8375503}. Cytoplasmic vesicle membrane {ECO:0000269|PubMed:15528189, ECO:0000269|PubMed:8294494}; Lipid-anchor {ECO:0000305|PubMed:8375503}; Cytoplasmic side {ECO:0000305|PubMed:8375503}. Cell junction, tight junction {ECO:0000269|PubMed:12058051, ECO:0000269|PubMed:8294494}. Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:18779367}. Recycling endosome membrane {ECO:0000269|PubMed:18779367}. Cell projection, lamellipodium {ECO:0000250|UniProtKB:Q9DD03}. Note=Tight junctions or associated with vesicles scattered throughout the cytoplasm in cells lacking tight junctions (PubMed:8294494). Relocalizes to the leading edge of lamellipodia in migrating endothelial cells (By similarity). {ECO:0000250|UniProtKB:Q9DD03, ECO:0000269|PubMed:8294494}. |
| Mouse PG classification | NA |
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