| Gene Information | |
|---|---|
| Gene Name | GPR65 |
| Organism | Homo sapiens (Human) |
| Gene Length | 337 |
| Protein Names | Psychosine receptor (G-protein coupled receptor 65) (T-cell death-associated gene 8 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000140030 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8IYL9 |
| Gene Card | GPR65 |
| Uniprot ID | Q8IYL9 |
| Pfam | PF00001 |
| In ASD | yes |
| Allosteric Prediction | yes (0.446115163) |
| Ortholog in Animals | Alpaca_ GPR65 ( ortholog_one2one ) Dog_ GPR65 ( ortholog_one2one ) GuineaPig_ GPR65 ( ortholog_one2one ) Macaque_ GPR65 ( ortholog_one2one ) Mouse_ Gpr65 ( ortholog_one2one ) Pig_ GPR65 ( ortholog_one2one ) Rat_ Gpr65 ( ortholog_one2one ) Rabbit_ GPR65 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | GPR20, LPAR4, LPAR6, P2RY10, GPR35, GPR55, F2RL2, P2RY8, F2RL1, F2R, F2RL3, GPR4, GPR18, CYSLTR2, GPR17, CYSLTR1 |
| Tissue | NA |
| Tissue Specificity | Predominantly expressed in thymus, spleen, lymph nodes, small intestine, lung, placenta and peripheral blood leukocytes. {ECO:0000269|PubMed:11309421, ECO:0000269|PubMed:9655242}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs3742704 |
| Subcellular location [CC] | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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