| Gene Information | |
|---|---|
| Gene Name | GPR63 |
| Organism | Homo sapiens (Human) |
| Gene Length | 419 |
| Protein Names | Probable G-protein coupled receptor 63 (PSP24-2) (PSP24-beta) |
| Target Name | g-protein coupled receptor 63 |
| Target Type | Literature-reported target |
| Gene Age | 645 ( ENSG00000112218 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9BZJ6 |
| Gene Card | GPR63 |
| Uniprot ID | Q9BZJ6 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | no (-1.257728942) |
| Ortholog in Animals | Alpaca_ GPR63 ( ortholog_one2one ) Dog_ GPR63 ( ortholog_one2one ) GuineaPig_ GPR63 ( ortholog_one2one ) Macaque_ GPR63 ( ortholog_one2one ) Mouse_ Gpr63 ( ortholog_one2one ) Pig_ GPR63 ( ortholog_one2one ) Rat_ Gpr63 ( ortholog_one2one ) Rabbit_ GPR63 ( ortholog_one2one ) |
| Ohnologs | GPR45 |
| Paralogs | GPR45, GPR78, GPR26 |
| Tissue | NA |
| Tissue Specificity | Expressed in brain; detected in the frontal cortex, with lower levels in the thalamus, caudate, hypothalamus and midbrain. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs35358396 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
| click here to return to the previous page | |