| Gene Information | |
|---|---|
| Gene Name | GPR62 |
| Organism | Homo sapiens (Human) |
| Gene Length | 368 |
| Protein Names | G-protein coupled receptor 62 (G-protein coupled receptor GPCR8) (hGPCR8) (G-protein coupled receptor KPG_005) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 3 ( ENSG00000180929 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q9BZJ7 |
| Gene Card | GPR62 |
| Uniprot ID | Q9BZJ7 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | no (-0.528969523) |
| Ortholog in Animals | Dog_ GPR62 ( ortholog_one2one ) GuineaPig_ GPR62 ( ortholog_one2one ) Macaque_ GPR62 ( ortholog_one2one ) Mouse_ Gpr62 ( ortholog_one2one ) Pig_ GPR62 ( ortholog_one2one ) Rat_ Gpr62 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | GPR61, GPR135, GPR176 |
| Tissue | NA |
| Tissue Specificity | Expressed in brain; detected in the basal forebrain, frontal cortex, caudate, putamen, thalamus and hippocampus. {ECO:0000269|PubMed:11165367}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs28587738 rs28651222 rs323871 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:28827538}; Multi-pass membrane protein {ECO:0000255}. Endosome membrane {ECO:0000269|PubMed:28827538}; Multi-pass membrane protein {ECO:0000255}. Note=Colocalizes with ARRB2 in the endosome (PubMed:28827538). {ECO:0000269|PubMed:28827538}. |
| Mouse PG classification | NA |
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