Gene Information
Gene NamePREP
OrganismHomo sapiens (Human)
Gene Length710
Protein NamesProlyl endopeptidase (PE) (EC 3.4.21.26) (Post-proline cleaving enzyme)
Target Nameprolyl endopeptidase
Target TypeNA
Gene Age1714 ( ENSG00000085377 )
Evolutionary StageEuk+Bac
AlphaFoldDBP48147
Gene CardPREP
Uniprot IDP48147
PfamPF00326; PF02897
In ASDno
Allosteric Predictionyes (1.089852246)
Ortholog in AnimalsAlpaca_ PREP ( ortholog_one2one )
Dog_ PREP ( ortholog_one2one )
GuineaPig_ PREP ( ortholog_one2one )
Macaque_ PREP ( ortholog_one2one )
Mouse_ Prep ( ortholog_one2one )
Pig_ PREP ( ortholog_one2one )
Rat_ Prep ( ortholog_one2one )
Rabbit_ PREP ( ortholog_one2one )
OhnologsNA
ParalogsPREPL
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 3DDU  (X-ray  1.56A 
DBSNP rs12192054  rs1051484 
Subcellular location [CC]Cytoplasm.
Mouse PG classificationNA
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