| Gene Information | |
|---|---|
| Gene Name | LIPN |
| Organism | Homo sapiens (Human) |
| Gene Length | 398 |
| Protein Names | Lipase member N (EC 3.1.1.-) (Lipase-like abhydrolase domain-containing protein 4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000204020 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q5VXI9 |
| Gene Card | LIPN |
| Uniprot ID | Q5VXI9 |
| Pfam | PF00561 |
| In ASD | no |
| Allosteric Prediction | no (-0.951170068) |
| Ortholog in Animals | Alpaca_ LIPN ( ortholog_one2one ) Dog_ LIPN ( ortholog_one2one ) GuineaPig_ LIPN ( ortholog_one2one ) Macaque_ LIPN ( ortholog_one2one ) Mouse_ Lipn ( ortholog_one2one ) Pig_ LIPN ( ortholog_one2one ) Rat_ Lipn ( ortholog_one2one ) Rabbit_ LIPN ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | LIPJ, LIPM, LIPF, LIPK, LIPA |
| Tissue | skin |
| Tissue Specificity | Highly expressed in the epidermis in the granular keratinocytes. Also detected in other tissues, although at much lower levels, including lung and spleen. {ECO:0000269|PubMed:17562024, ECO:0000269|PubMed:21439540}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs10788611 |
| Subcellular location [CC] | Secreted {ECO:0000305}. |
| Mouse PG classification | NA |
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