| Gene Information | |
|---|---|
| Gene Name | SCARB1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 552 |
| Protein Names | Scavenger receptor class B member 1 (SRB1) (CD36 and LIMPII analogous 1) (CLA-1) (CD36 antigen-like 1) (Collagen type I receptor, thrombospondin receptor-like 1) (SR-BI) (CD antigen CD36) |
| Target Name | scavenger receptor class b member 1 |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000073060 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8WTV0 |
| Gene Card | SCARB1 |
| Uniprot ID | Q8WTV0 |
| Pfam | PF01130 |
| In ASD | no |
| Allosteric Prediction | yes (0.705344814) |
| Ortholog in Animals | Alpaca_ SCARB1 ( ortholog_one2one ) Dog_ SCARB1 ( ortholog_one2one ) GuineaPig_ SCARB1 ( ortholog_one2one ) Macaque_ SCARB1 ( ortholog_one2one ) Mouse_ Scarb1 ( ortholog_one2one ) Pig_ SCARB1 ( ortholog_one2one ) Rat_ Scarb1 ( ortholog_one2one ) Rabbit_ SCARB1 ( ortholog_one2one ) |
| Ohnologs | CD36 |
| Paralogs | CD36, SCARB2 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs4238001 rs5891 rs199588922 rs10396213 rs387906791 rs74830677 rs2293440 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:26965621}; Multi-pass membrane protein. Membrane, caveola {ECO:0000250|UniProtKB:Q61009}; Multi-pass membrane protein. Note=Predominantly localized to cholesterol and sphingomyelin-enriched domains within the plasma membrane, called caveolae. |
| Mouse PG classification | NA |
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