| Gene Information | |
|---|---|
| Gene Name | GPR40 |
| Organism | Homo sapiens (Human) |
| Gene Length | 300 |
| Protein Names | Free fatty acid receptor 1 (G-protein coupled receptor 40) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O14842 |
| Gene Card | FFAR1 |
| Uniprot ID | O14842 |
| Pfam | PF00001 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Detected in brain and pancreas. Detected in pancreatic beta cells. {ECO:0000269|PubMed:12496284, ECO:0000269|PubMed:16289108}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4PHU (X-ray 2.33A ) 5KW2 (X-ray 2.76A ) 5TZR (X-ray 2.20A ) 5TZY (X-ray 3.22A ) |
| DBSNP | rs2301151 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:17699519, ECO:0000269|PubMed:25043059}; Multi-pass membrane protein {ECO:0000269|PubMed:25043059}. |
| Mouse PG classification | NA |
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