| Gene Information | |
|---|---|
| Gene Name | PLCH1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1693 |
| Protein Names | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-eta-1) (Phospholipase C-eta-1) (PLC-eta-1) (Phospholipase C-like protein 3) (PLC-L3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000114805 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q4KWH8 |
| Gene Card | PLCH1 |
| Uniprot ID | Q4KWH8 |
| Pfam | PF00168; PF09279; PF00388; PF00387 |
| In ASD | no |
| Allosteric Prediction | no (-0.175787566) |
| Ortholog in Animals | Alpaca_ PLCH1 ( ortholog_one2one ) Dog_ PLCH1 ( ortholog_one2one ) GuineaPig_ PLCH1 ( ortholog_one2one ) Macaque_ PLCH1 ( ortholog_one2one ) Mouse_ Plch1 ( ortholog_one2one ) Pig_ PLCH1 ( ortholog_one2one ) Rat_ Plch1 ( ortholog_one2one ) Rabbit_ PLCH1 ( ortholog_one2one ) |
| Ohnologs | PLCH2 |
| Paralogs | PLCG2, PLCD3, PLCB3, PLCE1, PLCG1, PLCB1, PLCD4, PLCD1, PLCB2, PLCB4, PLCL2, PLCL1, PLCZ1, PLCH2 |
| Tissue | testis |
| Tissue Specificity | Expressed in brain and to a lower extent in lung. In brain, it is found in cerebrum, cerebellum and spinal cord. {ECO:0000269|PubMed:15702972}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:15702972}. Membrane {ECO:0000269|PubMed:15702972}. |
| Mouse PG classification | NA |
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