| Gene Information | |
|---|---|
| Gene Name | KSR2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1034 |
| Protein Names | Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR 2) (CNK homolog protein 2) (CNK2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000171435 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8WXI2 |
| Gene Card | CNKSR2 |
| Uniprot ID | Q8WXI2 |
| Pfam | PF06663; PF10534; PF00595; PF00169; PF00536 |
| In ASD | no |
| Allosteric Prediction | yes (0.742789236) |
| Ortholog in Animals | Alpaca_ KSR2 ( ortholog_one2one ) Dog_ KSR2 ( ortholog_one2one ) GuineaPig_ KSR2 ( ortholog_one2one ) Macaque_ KSR2 ( ortholog_one2one ) Mouse_ Ksr2 ( ortholog_one2one ) Pig_ KSR2 ( ortholog_one2one ) Rat_ Ksr2 ( ortholog_one2one ) Rabbit_ KSR2 ( ortholog_one2one ) |
| Ohnologs | KSR1 |
| Paralogs | LIMK2, RIPK1, LRRK2, TNNI3K, TESK2, MAP3K10, RIPK2, MOS, MAP3K9, MLKL, MAP3K20, ARAF, TESK1, MAP3K13, BRAF, ILK, MAP3K11, RAF1, MAP3K12, MAP3K21, LIMK1, KSR1, RIPK3 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 2EAN (NMR - ) 3BS5 (X-ray 2.00A ) |
| DBSNP | rs771705122 |
| Subcellular location [CC] | Cytoplasm. Membrane; Peripheral membrane protein. |
| Mouse PG classification | NA |
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