| Gene Information | |
|---|---|
| Gene Name | GPR37L1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 481 |
| Protein Names | G-protein coupled receptor 37-like 1 (Endothelin B receptor-like protein 2) (ETBR-LP-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000170075 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O60883 |
| Gene Card | GPR37L1 |
| Uniprot ID | O60883 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | yes (0.543527248) |
| Ortholog in Animals | Alpaca_ GPR37L1 ( ortholog_one2one ) Dog_ GPR37L1 ( ortholog_one2one ) GuineaPig_ GPR37L1 ( ortholog_one2one ) Macaque_ GPR37L1 ( ortholog_one2one ) Mouse_ Gpr37l1 ( ortholog_one2one ) Pig_ GPR37L1 ( ortholog_one2one ) Rat_ Gpr37l1 ( ortholog_one2one ) |
| Ohnologs | GPR37 |
| Paralogs | NTSR1, GHSR, NMUR2, NTSR2, GPR39, NMUR1, MLNR, BRS3, NMBR, EDNRA, GRPR, EDNRB, GPR37, GPR148, TRHR |
| Tissue | brain, cerebral.cortex |
| Tissue Specificity | Expressed in primary cortical astrocytes (at protein level) (PubMed:23690594). Expressed in the central nervous system (PubMed:9539149). {ECO:0000269|PubMed:23690594, ECO:0000269|PubMed:9539149}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3795594 rs3795595 rs17854616 rs372386575 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:28688853}; Multi-pass membrane protein {ECO:0000255}. Cell projection, cilium membrane {ECO:0000250|UniProtKB:Q99JG2}; Multi-pass membrane protein {ECO:0000255}. Note=Associates with the basal membrane of Bergmann glia cell primary cilia. {ECO:0000250|UniProtKB:Q99JG2}. |
| Mouse PG classification | NA |
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