| Gene Information | |
|---|---|
| Gene Name | MPFYVE |
| Organism | Homo sapiens (Human) |
| Gene Length | 471 |
| Protein Names | Abscission/NoCut checkpoint regulator (ANCHR) (MLL partner containing FYVE domain) (Zinc finger FYVE domain-containing protein 19) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q96K21 |
| Gene Card | ZFYVE19 |
| Uniprot ID | Q96K21 |
| Pfam | PF01363 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Detected in brain, heart, skeletal muscle and kidney (PubMed:12618766). Expressed in the liver (at protein level) (PubMed:12618766, PubMed:32737136). {ECO:0000269|PubMed:12618766, ECO:0000269|PubMed:32737136}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.009624(Mouse);0.001000(Rat);0.016667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1215965232 rs769683740 rs771251472 rs34819163 rs375497733 rs690347 rs72735636 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:24814515}. Cleavage furrow {ECO:0000269|PubMed:24814515}. Midbody, Midbody ring {ECO:0000269|PubMed:24814515}. Note=Localizes mainly on centrosomes in interphase and early mitosis. Localizes at the cleavage furrow and midbody ring in late mitosis and cytokinesis. {ECO:0000269|PubMed:24814515}. |
| Mouse PG classification | NA |
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