| Gene Information | |
|---|---|
| Gene Name | GPR27 |
| Organism | Homo sapiens (Human) |
| Gene Length | 375 |
| Protein Names | Probable G-protein coupled receptor 27 (Super conserved receptor expressed in brain 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 78 ( ENSG00000170837 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9NS67 |
| Gene Card | GPR27 |
| Uniprot ID | Q9NS67 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | yes (0.532203363) |
| Ortholog in Animals | Alpaca_ GPR27 ( ortholog_one2one ) Dog_ GPR27 ( ortholog_one2one ) Macaque_ GPR27 ( ortholog_one2one ) Mouse_ Gpr27 ( ortholog_one2one ) Pig_ GPR27 ( ortholog_one2one ) Rat_ Gpr27 ( ortholog_one2one ) |
| Ohnologs | GPR85, GPR173 |
| Paralogs | GPR173, GPR85 |
| Tissue | NA |
| Tissue Specificity | Highly expressed as a 3.0 kb transcript in brain, ovary, testis, heart, prostate and peripheral Leukocytes. Lower levels in pancreas and small intestine. A 2.3 kb transcript was also found in peripheral Leukocytes. In brain regions, detected as a 3.0 kb transcript in all regions tested. Highest levels in the caudate nucleus, putamen, hippocampus and subthalamic nucleus. Lowest level in the cerebellum. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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