| Gene Information | |
|---|---|
| Gene Name | GPR26 |
| Organism | Homo sapiens (Human) |
| Gene Length | 337 |
| Protein Names | G-protein coupled receptor 26 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000154478 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8NDV2 |
| Gene Card | GPR26 |
| Uniprot ID | Q8NDV2 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | yes (0.402590582) |
| Ortholog in Animals | Alpaca_ GPR26 ( ortholog_one2one ) Dog_ GPR26 ( ortholog_one2one ) GuineaPig_ GPR26 ( ortholog_one2one ) Macaque_ GPR26 ( ortholog_one2one ) Mouse_ Gpr26 ( ortholog_one2one ) Pig_ GPR26 ( ortholog_one2one ) Rat_ Gpr26 ( ortholog_one2one ) Rabbit_ GPR26 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | GPR78, GPR63, GPR45 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in the CNS, the highest expression is seen in the amygdala, hippocampus and thalamus. Weak expression is detected in testis. Down-regulated in glioblastoma. {ECO:0000269|PubMed:17363172, ECO:0000269|PubMed:18037267}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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