| Gene Information | |
|---|---|
| Gene Name | CCDC120 |
| Organism | Homo sapiens (Human) |
| Gene Length | 630 |
| Protein Names | Coiled-coil domain-containing protein 120 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000147144 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q96HB5 |
| Gene Card | CCDC120 |
| Uniprot ID | Q96HB5 |
| Pfam | PF11819 |
| In ASD | no |
| Allosteric Prediction | no (-0.89154287) |
| Ortholog in Animals | Alpaca_ CCDC120 ( ortholog_one2one ) Dog_ CCDC120 ( ortholog_one2one ) GuineaPig_ CCDC120 ( ortholog_one2one ) Macaque_ CCDC120 ( ortholog_one2one ) Mouse_ Ccdc120 ( ortholog_one2one ) Pig_ CCDC120 ( ortholog_one2one ) Rat_ Ccdc120 ( ortholog_one2one ) Rabbit_ CCDC120 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | INAVA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:28422092}. Cytoplasm {ECO:0000269|PubMed:25326380}. Cell projection, neuron projection {ECO:0000269|PubMed:25326380}. Cell projection, growth cone {ECO:0000269|PubMed:25326380}. Endosome {ECO:0000269|PubMed:25326380}. Note=Localizes to the subdistal appendages of mother centrioles and proximal ends of both centrioles in interphase cells (PubMed:28422092). Recruited to subdistal appendages by ODF2 (PubMed:28422092). In differentiating neuroblastoma cells, colocalizes with CYTH2 in both neurite shaft and growth cone areas (PubMed:25326380). Partially colocalizes with endosomes along neurites in differentiating neuroblastoma cells (PubMed:25326380). {ECO:0000269|PubMed:25326380, ECO:0000269|PubMed:28422092}. |
| Mouse PG classification | NA |
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