| Gene Information | |
|---|---|
| Gene Name | CELSR2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 2923 |
| Protein Names | Cadherin EGF LAG seven-pass G-type receptor 2 (Cadherin family member 10) (Epidermal growth factor-like protein 2) (EGF-like protein 2) (Flamingo homolog 3) (Multiple epidermal growth factor-like domains protein 3) (Multiple EGF-like domains protein 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000143126 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | NA |
| Gene Card | CELSR2 |
| Uniprot ID | Q9HCU4 |
| Pfam | PF00002; PF00028; PF00008; PF16489; PF01825; PF12661; PF00053; PF02210 |
| In ASD | no |
| Allosteric Prediction | no (-0.98412012) |
| Ortholog in Animals | Alpaca_ CELSR2 ( ortholog_one2one ) Dog_ CELSR2 ( ortholog_one2one ) GuineaPig_ CELSR2 ( ortholog_one2one ) Macaque_ CELSR2 ( ortholog_one2one ) Mouse_ Celsr2 ( ortholog_one2one ) Pig_ CELSR2 ( ortholog_one2one ) Rat_ Celsr2 ( ortholog_one2one ) Rabbit_ CELSR2 ( ortholog_one2one ) |
| Ohnologs | CELSR3, CELSR1 |
| Paralogs | CELSR3, FAT2, FAT1, CELSR1, FAT4, FAT3 |
| Tissue | brain, testis |
| Tissue Specificity | Highest expression in brain and testis. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12083590 rs653635 rs12567377 rs17035649 rs149683589 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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