Gene Information
Gene NameTMEM237
OrganismHomo sapiens (Human)
Gene Length408
Protein NamesTransmembrane protein 237 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein)
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000155755 )
Evolutionary StageVertebrata
AlphaFoldDBQ96Q45
Gene CardTMEM237
Uniprot IDQ96Q45
PfamPF15383
In ASDno
Allosteric Predictionno (-1.532010745)
Ortholog in AnimalsAlpaca_ TMEM237 ( ortholog_one2one )
Dog_ TMEM237 ( ortholog_one2one )
GuineaPig_ TMEM237 ( ortholog_one2one )
Macaque_ TMEM237 ( ortholog_one2one )
Mouse_ Tmem237 ( ortholog_one2one )
Pig_ TMEM237 ( ortholog_one2one )
Rat_ Tmem237 ( ortholog_one2one )
Rabbit_ TMEM237 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Membrane {ECO:0000305};
Multi-pass membrane protein {ECO:0000305}. Cell projection, cilium {ECO:0000269|PubMed:22152675}. Note=Localizes at the proximal region of primary cilia were observed, consistent with localization to the transition zone. Anchored to the transition zone by RPGRIP1L.
Mouse PG classificationNA
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