| Gene Information | |
|---|---|
| Gene Name | PDHX |
| Organism | Homo sapiens (Human) |
| Gene Length | 501 |
| Protein Names | Pyruvate dehydrogenase protein X component, mitochondrial (Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex) (E3-binding protein) (E3BP) (Lipoyl-containing pyruvate dehydrogenase complex component X) (proX) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000110435 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | O00330 |
| Gene Card | PDHX |
| Uniprot ID | O00330 |
| Pfam | PF00198; PF00364; PF02817 |
| In ASD | no |
| Allosteric Prediction | yes (0.121270372) |
| Ortholog in Animals | Alpaca_ PDHX ( ortholog_one2one ) Dog_ PDHX ( ortholog_one2one ) GuineaPig_ PDHX ( ortholog_one2one ) Macaque_ PDHX ( ortholog_one2one ) Mouse_ Pdhx ( ortholog_one2one ) Pig_ PDHX ( ortholog_one2one ) Rat_ Pdhx ( ortholog_one2one ) Rabbit_ PDHX ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DBT, DLST, DLAT |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.053256(Rat);0.197862(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1ZY8 (X-ray 2.59A ) 2DNC (NMR - ) 2F5Z (X-ray 2.18A ) 2F60 (X-ray 1.55A ) 6H60 (EM 6.00A ) |
| DBSNP | rs1049306 rs11539202 rs17850649 |
| Subcellular location [CC] | Mitochondrion matrix. |
| Mouse PG classification | NA |
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