| Gene Information | |
|---|---|
| Gene Name | CTSW |
| Organism | Homo sapiens (Human) |
| Gene Length | 376 |
| Protein Names | Cathepsin W (EC 3.4.22.-) (Lymphopain) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000172543 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P56202 |
| Gene Card | CTSW |
| Uniprot ID | P56202 |
| Pfam | PF08246; PF00112 |
| In ASD | no |
| Allosteric Prediction | no (-0.260768932) |
| Ortholog in Animals | Alpaca_ CTSW ( ortholog_one2one ) Dog_ CTSW ( ortholog_one2one ) GuineaPig_ CTSW ( ortholog_one2one ) Macaque_ CTSW ( ortholog_one2one ) Mouse_ Ctsw ( ortholog_one2one ) Pig_ CTSW ( ortholog_one2one ) Rat_ Ctsw ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CTSL, CTSV, CTSK, CTSH, TINAGL1, CTSO, CTSF, TINAG, CTSB, CTSC, CTSZ, CTSS |
| Tissue | whole.blood |
| Tissue Specificity | Expressed predominantly in natural killer cells, and in cytotoxic T cells. {ECO:0000269|PubMed:11490002}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs604630 rs606830 |
| Subcellular location [CC] | Endoplasmic reticulum {ECO:0000269|PubMed:11490002}. |
| Mouse PG classification | NA |
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