| Gene Information | |
|---|---|
| Gene Name | NPFFR1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 430 |
| Protein Names | Neuropeptide FF receptor 1 (G-protein coupled receptor 147) (RFamide-related peptide receptor OT7T022) |
| Target Name | neuropeptide ff receptor 1 |
| Target Type | Literature-reported target |
| Gene Age | 645 ( ENSG00000148734 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9GZQ6 |
| Gene Card | NPFFR1 |
| Uniprot ID | Q9GZQ6 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | yes (0.727621444) |
| Ortholog in Animals | Alpaca_ NPFFR1 ( ortholog_one2one ) Dog_ NPFFR1 ( ortholog_one2one ) GuineaPig_ NPFFR1 ( ortholog_one2one ) Macaque_ NPFFR1 ( ortholog_one2one ) Mouse_ Npffr1 ( ortholog_one2one ) Pig_ NPFFR1 ( ortholog_one2one ) Rat_ Npffr1 ( ortholog_one2one ) Rabbit_ NPFFR1 ( ortholog_one2one ) |
| Ohnologs | NPFFR2, NPY2R |
| Paralogs | NPFFR2, HCRTR2, HCRTR1, CCKBR, CCKAR, OXTR, AVPR2, AVPR1B, AVPR1A, GNRHR, GALR3, GPR22, GPR150, FFAR4, GALR1, QRFPR |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3812694 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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