Gene Information
Gene NameGPR142
OrganismHomo sapiens (Human)
Gene Length462
Protein NamesProbable G-protein coupled receptor 142 (G-protein coupled receptor PGR2)
Target NameNA
Target TypeNA
Gene Age544 ( ENSG00000257008 )
Evolutionary StageNA
AlphaFoldDBQ7Z601
Gene CardGPR142
Uniprot IDQ7Z601
PfamPF00001
In ASDno
Allosteric Predictionno (-0.264729362)
Ortholog in AnimalsAlpaca_ GPR142 ( ortholog_one2one )
Dog_ GPR142 ( ortholog_one2one )
GuineaPig_ GPR142 ( ortholog_one2one )
Macaque_ GPR142 ( ortholog_one2one )
Mouse_ Gpr142 ( ortholog_one2one )
Pig_ GPR142 ( ortholog_one2one )
Rat_ Gpr142 ( ortholog_one2one )
Rabbit_ GPR142 ( ortholog_one2one )
OhnologsNA
ParalogsGPR139
TissueNA
Tissue SpecificityExclusively expressed in the central nervous system, most abundantly in the ventrolateral region of caudate putamen, the habenular nucleus, the zona incerta, and the medial mammillary nucleus. {ECO:0000269|PubMed:15845401}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs2382647 
Subcellular location [CC]Cell membrane;
Multi-pass membrane protein.
Mouse PG classificationNA
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