| Gene Information | |
|---|---|
| Gene Name | GPR13 |
| Organism | Homo sapiens (Human) |
| Gene Length | 355 |
| Protein Names | CX3C chemokine receptor 1 (C-X3-C CKR-1) (CX3CR1) (Beta chemokine receptor-like 1) (CMK-BRL-1) (CMK-BRL1) (Fractalkine receptor) (G-protein coupled receptor 13) (V28) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P49238 |
| Gene Card | CX3CR1 |
| Uniprot ID | P49238 |
| Pfam | PF00001 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in lymphoid and neural tissues (PubMed:7590284). Expressed in lymphocyte subsets, such as natural killer (NK) cells, gamma-delta T-cells and terminally differentiated CD8(+) T-cells (PubMed:12055230). Expressed in smooth muscle cells in atherosclerotic plaques (PubMed:14581400). {ECO:0000269|PubMed:12055230, ECO:0000269|PubMed:14581400, ECO:0000269|PubMed:7590284}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7XBW (EM 2.80A ) 7XBX (EM 3.40A ) |
| DBSNP | rs41535248 rs199811198 rs143001773 rs3732380 rs3732379 rs3732378 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:12055230, ECO:0000269|PubMed:28791023, ECO:0000269|PubMed:9390561}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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