| Gene Information | |
|---|---|
| Gene Name | GPR124 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1338 |
| Protein Names | Adhesion G protein-coupled receptor A2 (G-protein coupled receptor 124) (Tumor endothelial marker 5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q96PE1 |
| Gene Card | ADGRA2 |
| Uniprot ID | Q96PE1 |
| Pfam | PF00002; PF01825; PF13855 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in endothelial cells (at protein level) (PubMed:15021905, PubMed:16982628). Abundantly expressed in heart, placenta, ovary, small intestine, and colon (PubMed:15021905). {ECO:0000269|PubMed:15021905, ECO:0000269|PubMed:16982628}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:16982628, ECO:0000269|PubMed:21421844, ECO:0000269|PubMed:22013897}; Multi-pass membrane protein {ECO:0000255}. Cell projection, filopodium {ECO:0000269|PubMed:21421844}. Note=Enriched at lateral cell borders and also at sites of cell-ECM (extracellular matrix) contact. {ECO:0000269|PubMed:21421844}. |
| Mouse PG classification | NA |
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