| Gene Information | |
|---|---|
| Gene Name | GPM6B |
| Organism | Homo sapiens (Human) |
| Gene Length | 265 |
| Protein Names | Neuronal membrane glycoprotein M6-b (M6b) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 810 ( ENSG00000046653 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q13491 |
| Gene Card | GPM6B |
| Uniprot ID | Q13491 |
| Pfam | PF01275 |
| In ASD | no |
| Allosteric Prediction | no (-0.331576484) |
| Ortholog in Animals | Alpaca_ GPM6B ( ortholog_one2one ) Dog_ GPM6B ( ortholog_one2one ) GuineaPig_ GPM6B ( ortholog_one2one ) Macaque_ GPM6B ( ortholog_one2one ) Mouse_ Gpm6b ( ortholog_one2one ) Rat_ Gpm6b ( ortholog_one2one ) |
| Ohnologs | PLP1, GPM6A |
| Paralogs | PLP1, GPM6A |
| Tissue | NA |
| Tissue Specificity | Neurons and glia; cerebellar Bergmann glia, in glia within white matter tracts of the cerebellum and cerebrum, and in embryonic dorsal root ganglia. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Colocalizes with SERT at the plasma membrane. {ECO:0000250}. |
| Mouse PG classification | NA |
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