| Gene Information | |
|---|---|
| Gene Name | RTN4IP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 396 |
| Protein Names | Reticulon-4-interacting protein 1, mitochondrial (NOGO-interacting mitochondrial protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000130347 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q8WWV3 |
| Gene Card | RTN4IP1 |
| Uniprot ID | Q8WWV3 |
| Pfam | PF08240 |
| In ASD | no |
| Allosteric Prediction | no (-1.005297108) |
| Ortholog in Animals | Alpaca_ RTN4IP1 ( ortholog_one2one ) Dog_ RTN4IP1 ( ortholog_one2one ) GuineaPig_ RTN4IP1 ( ortholog_one2one ) Macaque_ RTN4IP1 ( ortholog_one2one ) Mouse_ Rtn4ip1 ( ortholog_one2one ) Pig_ RTN4IP1 ( ortholog_one2one ) Rat_ Rtn4ip1 ( ortholog_one2one ) Rabbit_ RTN4IP1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MECR, CRYZ, PTGR2, TP53I3, CRYZL1, PTGR3, ADH6, ADH4, SORD, ADH1B, ADH1A, ADH1C, VAT1L, PTGR1, ADH5, ADH7, VAT1 |
| Tissue | NA |
| Tissue Specificity | Widely expressed in mitochondria-enriched tissues. Found in heart, muscle, kidney, liver, brain and placenta. {ECO:0000269|PubMed:12067236}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2VN8 (X-ray 2.10A ) |
| DBSNP | rs372054380 |
| Subcellular location [CC] | Mitochondrion outer membrane {ECO:0000269|PubMed:12067236, ECO:0000269|PubMed:26593267}. Note=Colocalizes with the endoplasmic reticulum HSPA5 at spots corresponding to contacts with mitochondria. {ECO:0000269|PubMed:26593267}. |
| Mouse PG classification | NA |
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