| Gene Information | |
|---|---|
| Gene Name | RNF5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 180 |
| Protein Names | E3 ubiquitin-protein ligase RNF5 (EC 2.3.2.27) (RING finger protein 5) (Ram1 homolog) (HsRma1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 3 ( ENSG00000183574 ) 544 ( ENSG00000204308 ) 3 ( ENSG00000223767 ) 3 ( ENSG00000225452 ) 3 ( ENSG00000227277 ) 3 ( ENSG00000228405 ) 3 ( ENSG00000228907 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q99942 |
| Gene Card | RNF5 |
| Uniprot ID | Q99942 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.455681389) |
| Ortholog in Animals | Alpaca_ RNF5 ( ortholog_one2many ) Dog_ RNF5 ( ortholog_one2one ) GuineaPig_ RNF5 ( ortholog_one2one ) Macaque_ RNF5 ( ortholog_one2one ) Mouse_ Rnf5 ( ortholog_one2one ) Pig_ RNF5 ( ortholog_one2one ) Rat_ Rnf5 ( ortholog_one2one ) Rabbit_ RNF5 ( ortholog_one2one ) |
| Ohnologs | RNF185 |
| Paralogs | RNF185 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:9533025}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:9533025}; Multi-pass membrane protein {ECO:0000255}. Mitochondrion membrane {ECO:0000269|PubMed:19285439}; Multi-pass membrane protein {ECO:0000255}. Endoplasmic reticulum membrane {ECO:0000269|PubMed:19285439}; Multi-pass membrane protein {ECO:0000255}. Note=Predominantly located in the plasma membrane, with some localization occurring within cytoplasmic organelles. {ECO:0000269|PubMed:9533025}. |
| Mouse PG classification | NA |
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