| Gene Information | |
|---|---|
| Gene Name | EDEM3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 932 |
| Protein Names | ER degradation-enhancing alpha-mannosidase-like protein 3 (EC 3.2.1.113) (Alpha-1,2-mannosidase EDEM3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000116406 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q9BZQ6 |
| Gene Card | EDEM3 |
| Uniprot ID | Q9BZQ6 |
| Pfam | PF01532; PF02225 |
| In ASD | no |
| Allosteric Prediction | no (-0.914961969) |
| Ortholog in Animals | Alpaca_ EDEM3 ( ortholog_one2one ) Dog_ EDEM3 ( ortholog_one2one ) GuineaPig_ EDEM3 ( ortholog_one2one ) Macaque_ EDEM3 ( ortholog_one2one ) Mouse_ Edem3 ( ortholog_one2one ) Pig_ EDEM3 ( ortholog_one2one ) Rat_ Edem3 ( ortholog_one2one ) Rabbit_ EDEM3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MAN1A2, MAN1A1, MAN1B1, EDEM1, EDEM2, MAN1C1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs777353823 rs902837579 rs9425343 |
| Subcellular location [CC] | Endoplasmic reticulum lumen {ECO:0000255|PROSITE-ProRule:PRU10138}. |
| Mouse PG classification | NA |
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