| Gene Information | |
|---|---|
| Gene Name | PFKL |
| Organism | Homo sapiens (Human) |
| Gene Length | 780 |
| Protein Names | ATP-dependent 6-phosphofructokinase, liver type (ATP-PFK) (PFK-L) (EC 2.7.1.11) (6-phosphofructokinase type B) (Phosphofructo-1-kinase isozyme B) (PFK-B) (Phosphohexokinase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000141959 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P17858 |
| Gene Card | PFKL |
| Uniprot ID | P17858 |
| Pfam | PF00365 |
| In ASD | yes |
| Allosteric Prediction | yes (0.5809274) |
| Ortholog in Animals | Alpaca_ PFKL ( ortholog_one2one ) Dog_ PFKL ( ortholog_one2one ) GuineaPig_ PFKL ( ortholog_one2one ) Macaque_ PFKL ( ortholog_one2one ) Mouse_ Pfkl ( ortholog_one2one ) Pig_ PFKL ( ortholog_one2one ) Rat_ Pfkl ( ortholog_one2one ) |
| Ohnologs | PFKP, PFKM |
| Paralogs | PFKP, PFKM |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.119412(Mouse);0.001000(Rat);0.110131(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7LW1 (EM 2.90A ) |
| DBSNP | rs755851304 rs1057037 |
| Subcellular location [CC] | Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03184}. |
| Mouse PG classification | NA |
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