| Gene Information | |
|---|---|
| Gene Name | GPI |
| Organism | Homo sapiens (Human) |
| Gene Length | 558 |
| Protein Names | Glucose-6-phosphate isomerase (GPI) (EC 5.3.1.9) (Autocrine motility factor) (AMF) (Neuroleukin) (NLK) (Phosphoglucose isomerase) (PGI) (Phosphohexose isomerase) (PHI) (Sperm antigen 36) (SA-36) |
| Target Name | glucose-6-phosphate isomerase |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000105220 ) 3 ( ENSG00000282019 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P06744 |
| Gene Card | GPI |
| Uniprot ID | P06744 |
| Pfam | PF00342 |
| In ASD | no |
| Allosteric Prediction | yes (1.09073903) |
| Ortholog in Animals | Alpaca_ GPI ( ortholog_one2one ) Dog_ GPI ( ortholog_one2many ) GuineaPig_ GPI ( ortholog_one2one ) Macaque_ GPI ( ortholog_one2one ) Mouse_ Gpi1 ( ortholog_one2one ) Pig_ GPI ( ortholog_one2one ) Rat_ Gpi ( ortholog_one2one ) Rabbit_ GPI ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1IAT (X-ray 1.62A ) 1IRI (X-ray 2.40A ) 1JIQ (X-ray 1.90A ) 1JLH (X-ray 2.10A ) 1NUH (X-ray 2.51A ) 6XUH (X-ray 2.38A ) 6XUI (X-ray 1.95A ) |
| DBSNP | rs267606852 rs137853586 rs1246980119 rs983725326 rs757341382 rs137853582 rs1426869331 rs8191371 rs61754634 rs1250029517 rs34306618 rs1435398228 rs2230294 rs137853587 rs267606851 rs758132799 rs137853583 rs267606853 rs139382538 rs1364382189 rs148811525 rs374583873 rs900848255 rs137853584 rs137853585 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:11437381}. Secreted {ECO:0000269|PubMed:11437381}. |
| Mouse PG classification | NA |
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