| Gene Information | |
|---|---|
| Gene Name | ESAM |
| Organism | Homo sapiens (Human) |
| Gene Length | 390 |
| Protein Names | Endothelial cell-selective adhesion molecule |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000149564 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96AP7 |
| Gene Card | ESAM |
| Uniprot ID | Q96AP7 |
| Pfam | PF07686 |
| In ASD | no |
| Allosteric Prediction | no (-0.778915527) |
| Ortholog in Animals | Alpaca_ ESAM ( ortholog_one2one ) Dog_ ESAM ( ortholog_one2one ) GuineaPig_ ESAM ( ortholog_one2one ) Macaque_ ESAM ( ortholog_one2one ) Mouse_ Esam ( ortholog_one2one ) Pig_ ESAM ( ortholog_one2one ) Rat_ Esam ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MXRA8, VSIG1, IGSF11, JAM3, VSIG2, JAM2, F11R, MUC15, GPA33, CXADR, VSTM2B, VSIR, VSIG8, CLMP |
| Tissue | NA |
| Tissue Specificity | Highly expressed in endothelial cells. {ECO:0000269|PubMed:11279107}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12792040 |
| Subcellular location [CC] | Cell junction, adherens junction {ECO:0000250}. Cell junction, tight junction {ECO:0000250}. Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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