| Gene Information | |
|---|---|
| Gene Name | CPEB4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 729 |
| Protein Names | Cytoplasmic polyadenylation element-binding protein 4 (CPE-BP4) (CPE-binding protein 4) (hCPEB-4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000113742 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q17RY0 |
| Gene Card | CPEB4 |
| Uniprot ID | Q17RY0 |
| Pfam | PF16366; PF16367 |
| In ASD | no |
| Allosteric Prediction | no (-0.045014478) |
| Ortholog in Animals | Alpaca_ CPEB4 ( ortholog_one2one ) Dog_ CPEB4 ( ortholog_one2one ) GuineaPig_ CPEB4 ( ortholog_one2one ) Macaque_ CPEB4 ( ortholog_one2one ) Mouse_ Cpeb4 ( ortholog_one2one ) Pig_ CPEB4 ( ortholog_one2one ) Rat_ Cpeb4 ( ortholog_one2one ) Rabbit_ CPEB4 ( ortholog_one2one ) |
| Ohnologs | CPEB3, CPEB2 |
| Paralogs | CPEB2, CPEB1, CPEB3 |
| Tissue | substantia.nigra |
| Tissue Specificity | Expressed in pancreas in islets and ductal cells (at protein level) (PubMed:22138752). Expressed in melanocytes (PubMed:27857118). {ECO:0000269|PubMed:22138752, ECO:0000269|PubMed:27857118}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 2MKI (NMR - ) 2MKJ (NMR - ) 5DIF (X-ray 2.09A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:Q7TN98}. Cell projection, dendrite {ECO:0000250|UniProtKB:Q7TN98}. Cell projection, dendritic spine {ECO:0000250|UniProtKB:Q7TN98}. Postsynaptic density {ECO:0000250|UniProtKB:Q7TN98}. Cell projection, axon {ECO:0000250|UniProtKB:Q7TN98}. Cell projection, growth cone {ECO:0000250|UniProtKB:Q7TN98}. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q7TN98}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q7TN98}. |
| Mouse PG classification | NA |
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