Gene Information
Gene NameGPD1
OrganismHomo sapiens (Human)
Gene Length349
Protein NamesGlycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic (GPD-C) (GPDH-C) (EC 1.1.1.8)
Target Nameglycerol-3-phosphate dehydrogenase [nad(+)], cytoplasmic
Target TypeNA
Gene Age454 ( ENSG00000167588 )
Evolutionary StageEuk+Bac
AlphaFoldDBP21695
Gene CardGPD1
Uniprot IDP21695
PfamPF07479; PF01210
In ASDyes
Allosteric Predictionno (-0.346116304)
Ortholog in AnimalsAlpaca_ GPD1 ( ortholog_one2one )
Dog_ GPD1 ( ortholog_one2one )
GuineaPig_ GPD1 ( ortholog_one2one )
Macaque_ GPD1 ( ortholog_one2one )
Mouse_ Gpd1 ( ortholog_one2one )
Pig_ GPD1 ( ortholog_one2one )
Rat_ Gpd1 ( ortholog_one2one )
OhnologsGPD1L
ParalogsGPD1L
TissueNA
Tissue SpecificityExpressed in liver (at protein level). {ECO:0000269|PubMed:7772607}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1WPQ  (X-ray  2.50A  1X0V  (X-ray  2.30A  1X0X  (X-ray  2.75A  6E8Y  (X-ray  1.85A  6E8Z  (X-ray  2.10A  6E90  (X-ray  2.05A  6PYP  (X-ray  1.95A 
DBSNP rs2232202  rs1128867  rs34783513  rs2232207  rs200251017  rs199673455 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:7772607}.
Mouse PG classificationNA
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