| Gene Information | |
|---|---|
| Gene Name | CNNM3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 707 |
| Protein Names | Metal transporter CNNM3 (Ancient conserved domain-containing protein 3) (Cyclin-M3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000168763 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8NE01 |
| Gene Card | CNNM3 |
| Uniprot ID | Q8NE01 |
| Pfam | PF00571 |
| In ASD | no |
| Allosteric Prediction | no (-1.320843417) |
| Ortholog in Animals | Alpaca_ CNNM3 ( ortholog_one2one ) Mouse_ Cnnm3 ( ortholog_one2one ) Pig_ CNNM3 ( ortholog_one2one ) Rat_ Cnnm3 ( ortholog_one2one ) |
| Ohnologs | CNNM1, CNNM2 |
| Paralogs | CNNM4, CNNM1, CNNM2 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Expressed at higher level in heart and spleen. {ECO:0000269|PubMed:12657465}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5K22 (X-ray 3.00A ) 5K23 (X-ray 2.96A ) 5K25 (X-ray 3.05A ) 5TSR (X-ray 3.19A ) 6DFD (X-ray 1.90A ) 6MN6 (X-ray 3.36A ) 6WUR (X-ray 2.88A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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