| Gene Information | |
|---|---|
| Gene Name | GPCR3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 451 |
| Protein Names | G-protein coupled receptor 61 (Biogenic amine receptor-like G-protein coupled receptor) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9BZJ8 |
| Gene Card | GPR61 |
| Uniprot ID | Q9BZJ8 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in brain; detected in frontal and temporal lobes, occipital pole, amygdala and hippocampus (PubMed:11690637, PubMed:29226084). Also expressed in testis (PubMed:11690637, PubMed:29226084) and T cells, B cells, and monocyte (PubMed:29226084). Low expression in many other tissues (PubMed:11690637, PubMed:29226084). Widely expressed in the hippocampus (at protein level). {ECO:0000269|PubMed:11690637, ECO:0000269|PubMed:29226084}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:28827538, ECO:0000269|PubMed:29226084}; Multi-pass membrane protein {ECO:0000255}. Endosome membrane {ECO:0000269|PubMed:28827538}; Multi-pass membrane protein {ECO:0000255}. Note=Colocalizes with ARRB2/beta-arrestin-2 in the endosome (PubMed:28827538). {ECO:0000269|PubMed:28827538}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |