| Gene Information | |
|---|---|
| Gene Name | GK2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 553 |
| Protein Names | Glycerol kinase 2 (GK 2) (Glycerokinase 2) (EC 2.7.1.30) (ATP:glycerol 3-phosphotransferase 2) (Glycerol kinase, testis specific 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000196475 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q14410 |
| Gene Card | GK2 |
| Uniprot ID | Q14410 |
| Pfam | PF02782; PF00370 |
| In ASD | no |
| Allosteric Prediction | no (-0.442855033) |
| Ortholog in Animals | Alpaca_ GK2 ( ortholog_one2one ) Dog_ GK2 ( ortholog_one2one ) Macaque_ GK2 ( ortholog_one2one ) Mouse_ Gk2 ( ortholog_one2one ) Pig_ GK2 ( ortholog_one2one ) Rat_ Gk2 ( ortholog_one2one ) Rabbit_ GK2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | GK3P, GK, GK5, XYLB, SHPK, FGGY |
| Tissue | testis |
| Tissue Specificity | Testis-specific (PubMed:33536340). Expressed in the midpiece of spermatozoa (PubMed:28852571). {ECO:0000269|PubMed:28852571, ECO:0000269|PubMed:33536340}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q9WU65}; Single-pass type IV membrane protein {ECO:0000250|UniProtKB:Q9WU65}. Cytoplasm {ECO:0000250}. Note=In sperm the majority of the enzyme is bound to mitochondria. {ECO:0000250|UniProtKB:Q9WU65}. |
| Mouse PG classification | NA |
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