| Gene Information | |
|---|---|
| Gene Name | GPC2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 579 |
| Protein Names | Glypican-2 [Cleaved into: Secreted glypican-2] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 810 ( ENSG00000213420 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8N158 |
| Gene Card | GPC2 |
| Uniprot ID | Q8N158 |
| Pfam | PF01153 |
| In ASD | no |
| Allosteric Prediction | no (-0.846942497) |
| Ortholog in Animals | Alpaca_ GPC2 ( ortholog_one2one ) Dog_ GPC2 ( ortholog_one2one ) GuineaPig_ GPC2 ( ortholog_one2one ) Macaque_ GPC2 ( ortholog_one2one ) Mouse_ Gpc2 ( ortholog_one2one ) Pig_ GPC2 ( ortholog_one2one ) Rat_ Gpc2 ( ortholog_one2one ) |
| Ohnologs | GPC4, GPC3, GPC5, GPC6, GPC1 |
| Paralogs | GPC4, GPC6, GPC1, GPC3, GPC5 |
| Tissue | testis, zone.of.skin |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6WJL (X-ray 3.30A ) 7T62 (EM 21.00A ) |
| DBSNP | rs1333017606 |
| Subcellular location [CC] | Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}; Extracellular side {ECO:0000250}.; [Secreted glypican-2]: Secreted, extracellular space {ECO:0000250}. |
| Mouse PG classification | NA |
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