| Gene Information | |
|---|---|
| Gene Name | PHKA2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1235 |
| Protein Names | Phosphorylase b kinase regulatory subunit alpha, liver isoform (Phosphorylase kinase alpha L subunit) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000044446 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P46019 |
| Gene Card | PHKA2 |
| Uniprot ID | P46019 |
| Pfam | PF00723; PF19292 |
| In ASD | no |
| Allosteric Prediction | yes (0.395749062) |
| Ortholog in Animals | Alpaca_ PHKA2 ( ortholog_one2one ) Dog_ PHKA2 ( ortholog_one2one ) GuineaPig_ PHKA2 ( ortholog_one2one ) Macaque_ PHKA2 ( ortholog_one2one ) Mouse_ Phka2 ( ortholog_one2one ) Pig_ PHKA2 ( ortholog_one2one ) Rat_ AABR07037995.1 ( ortholog_one2one ) Rabbit_ PHKA2 ( ortholog_one2one ) |
| Ohnologs | PHKA1 |
| Paralogs | PHKA1, PHKB |
| Tissue | NA |
| Tissue Specificity | Predominantly expressed in liver and other non-muscle tissues. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17313469 rs137852291 rs137852292 rs587776732 rs137852294 rs137852290 rs137852295 rs797044877 rs137852289 rs16980929 rs199792389 rs777137574 rs1569297427 rs1555989523 rs137852293 rs1555988071 rs137852288 |
| Subcellular location [CC] | Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. |
| Mouse PG classification | NA |
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