| Gene Information | |
|---|---|
| Gene Name | NCOA7 |
| Organism | Homo sapiens (Human) |
| Gene Length | 942 |
| Protein Names | Nuclear receptor coactivator 7 (140 kDa estrogen receptor-associated protein) (Estrogen nuclear receptor coactivator 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000111912 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8NI08 |
| Gene Card | NCOA7 |
| Uniprot ID | Q8NI08 |
| Pfam | PF01476; PF07534 |
| In ASD | no |
| Allosteric Prediction | no (-0.720695512) |
| Ortholog in Animals | Alpaca_ NCOA7 ( ortholog_one2one ) Dog_ NCOA7 ( ortholog_one2one ) GuineaPig_ NCOA7 ( ortholog_one2one ) Macaque_ NCOA7 ( ortholog_one2one ) Mouse_ Ncoa7 ( ortholog_one2one ) Pig_ NCOA7 ( ortholog_one2one ) Rat_ Ncoa7 ( ortholog_one2one ) Rabbit_ NCOA7 ( ortholog_one2one ) |
| Ohnologs | OXR1 |
| Paralogs | TLDC2, OXR1, MEAK7 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in brain. Weakly expressed in mammary gland, ovary, uterus, prostate, stomach, bladder, spinal cord and pancreas. Expressed in cancer cell line. {ECO:0000269|PubMed:11971969}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7OBP (X-ray 1.80A ) |
| DBSNP | rs6919947 rs35223550 rs1567 |
| Subcellular location [CC] | Nucleus {ECO:0000305}. |
| Mouse PG classification | NA |
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