| Gene Information | |
|---|---|
| Gene Name | GPAT4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 456 |
| Protein Names | Glycerol-3-phosphate acyltransferase 4 (EC 2.3.1.15) (1-acylglycerol-3-phosphate O-acyltransferase 6) (1-AGP acyltransferase 6) (1-AGPAT 6) (Acyl-CoA:glycerol-3-phosphate acyltransferase 4) (Lysophosphatidic acid acyltransferase zeta) (LPAAT-zeta) (Testis spermatogenesis apoptosis-related protein 7) (TSARG7) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000158669 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q86UL3 |
| Gene Card | GPAT4 |
| Uniprot ID | Q86UL3 |
| Pfam | PF01553 |
| In ASD | no |
| Allosteric Prediction | no (-0.631362413) |
| Ortholog in Animals | Alpaca_ GPAT4 ( ortholog_one2one ) Dog_ GPAT4 ( ortholog_one2one ) GuineaPig_ GPAT4 ( ortholog_one2one ) Macaque_ GPAT4 ( ortholog_one2one ) Mouse_ Gpat4 ( ortholog_one2one ) Pig_ GPAT4 ( ortholog_one2one ) Rat_ Gpat4 ( ortholog_one2one ) Rabbit_ GPAT4 ( ortholog_one2one ) |
| Ohnologs | GPAT3 |
| Paralogs | GPAT3, LPCAT2, LPCAT1, LPCAT4 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. High levels in testis. Relatively high level of expression in skeletal muscle and heart. Relatively low level of expression in lung. {ECO:0000269|PubMed:12938015, ECO:0000269|PubMed:16625827, ECO:0000269|PubMed:18238778}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:18238778}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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