| Gene Information | |
|---|---|
| Gene Name | GP1BA |
| Organism | Homo sapiens (Human) |
| Gene Length | 652 |
| Protein Names | Platelet glycoprotein Ib alpha chain (GP-Ib alpha) (GPIb-alpha) (GPIbA) (Glycoprotein Ibalpha) (Antigen CD42b-alpha) (CD antigen CD42b) [Cleaved into: Glycocalicin] |
| Target Name | platelet glycoprotein ib alpha chain |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000185245 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P07359 |
| Gene Card | GP1BA |
| Uniprot ID | P07359 |
| Pfam | PF13855; PF01462 |
| In ASD | no |
| Allosteric Prediction | yes (1.202913068) |
| Ortholog in Animals | Alpaca_ GP1BA ( ortholog_one2one ) Mouse_ Gp1ba ( ortholog_one2one ) Rat_ Gp1ba ( ortholog_one2one ) Rabbit_ GP1BA ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | LRTM1, LRRTM3, BGN, LRRTM1, LRRC19, RTN4RL2, LRRC4B, NYX, PODN, LRRC15, FLRT2, FLRT1, LRRTM4, LRRC66, RTN4RL1, LRRC4, ASPN, PODNL1, FLRT3, DCN, RTN4R, LRRC4C |
| Tissue | lymph.node, tonsil |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002657(Rat);0.072727(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 1GWB (X-ray 2.80A ) 1M0Z (X-ray 1.85A ) 1M10 (X-ray 3.10A ) 1OOK (X-ray 2.30A ) 1P8V (X-ray 2.60A ) 1P9A (X-ray 1.70A ) 1QYY (X-ray 2.80A ) 1SQ0 (X-ray 2.60A ) 1U0N (X-ray 2.95A ) 2BP3 (X-ray 2.32A ) 3P72 (X-ray 1.90A ) 3PMH (X-ray 3.20A ) 4C2A (X-ray 2.08A ) 4C2B (X-ray 2.80A ) 4CH2 (X-ray 1.60A ) 4CH8 (X-ray 1.75A ) 4MGX (X-ray 3.16A ) 4YR6 (X-ray 2.38A ) 6XFQ (X-ray 3.30A ) |
| DBSNP | rs6068 rs121908063 rs781541857 rs13306411 rs771048666 rs6065 rs121908065 rs1394634674 rs1597639057 rs121908062 rs382524 rs121908064 |
| Subcellular location [CC] | Membrane; Single-pass type I membrane protein. |
| Mouse PG classification | HPG |
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