| Gene Information | |
|---|---|
| Gene Name | GOPC |
| Organism | Homo sapiens (Human) |
| Gene Length | 462 |
| Protein Names | Golgi-associated PDZ and coiled-coil motif-containing protein (CFTR-associated ligand) (Fused in glioblastoma) (PDZ protein interacting specifically with TC10) (PIST) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000047932 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9HD26 |
| Gene Card | GOPC |
| Uniprot ID | Q9HD26 |
| Pfam | PF00595 |
| In ASD | no |
| Allosteric Prediction | no (-0.022184471) |
| Ortholog in Animals | Alpaca_ GOPC ( ortholog_one2one ) Dog_ GOPC ( ortholog_one2one ) GuineaPig_ GOPC ( ortholog_one2one ) Mouse_ Gopc ( ortholog_one2one ) Pig_ GOPC ( ortholog_one2one ) Rat_ Gopc ( ortholog_one2one ) Rabbit_ GOPC ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:11162552, ECO:0000269|PubMed:11384996, ECO:0000269|PubMed:11707463}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);NULL(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2DC2 (NMR - ) 2LOB (NMR - ) 4E34 (X-ray 1.40A ) 4E35 (X-ray 1.40A ) 4JOE (X-ray 1.14A ) 4JOF (X-ray 1.20A ) 4JOG (X-ray 1.46A ) 4JOH (X-ray 1.47A ) 4JOJ (X-ray 1.20A ) 4JOK (X-ray 1.09A ) 4JOP (X-ray 1.80A ) 4JOR (X-ray 1.34A ) 4K6Y (X-ray 1.48A ) 4K72 (X-ray 1.90A ) 4K75 (X-ray 1.50A ) 4K76 (X-ray 1.75A ) 4K78 (X-ray 1.80A ) 4NMO (X-ray 1.40A ) 4NMP (X-ray 1.30A ) 4NMQ (X-ray 1.40A ) 4NMR (X-ray 1.55A ) 4NMS (X-ray 1.70A ) 4NMT (X-ray 1.40A ) 4NMV (X-ray 1.40A ) 4Q6H (X-ray 1.90A ) 4Q6S (X-ray 1.45A ) 5IC3 (X-ray 1.70A ) 5K4F (X-ray 1.36A ) 6OV7 (X-ray 1.71A ) 6V84 (X-ray 1.64A ) 6XNJ (X-ray 1.85A ) 7JZO (X-ray 1.61A ) 7JZP (X-ray 1.95A ) 7JZQ (X-ray 1.35A ) 7JZR (X-ray 1.54A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm. Golgi apparatus membrane {ECO:0000269|PubMed:23818989}; Peripheral membrane protein. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Synapse {ECO:0000250}. Postsynaptic density {ECO:0000250}. Cell projection, dendrite {ECO:0000250}. Note=Enriched in synaptosomal and postsynaptic densities (PSD) fractions. Expressed in cell bodies and dendrites of Purkinje cells. Localized at the trans-Golgi network (TGN) of spermatids and the medulla of round spermatides. {ECO:0000250}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |