Gene Information
Gene NameSTX5
OrganismHomo sapiens (Human)
Gene Length355
Protein NamesSyntaxin-5
Target NameNA
Target TypeNA
Gene Age>4290 ( ENSG00000162236 )
Evolutionary StageEukaryota
AlphaFoldDBQ13190
Gene CardSTX5
Uniprot IDQ13190
PfamPF05739; PF11416
In ASDno
Allosteric Predictionno (-0.605583181)
Ortholog in AnimalsAlpaca_ STX5 ( ortholog_one2one )
Dog_ STX5 ( ortholog_one2one )
GuineaPig_ STX5 ( ortholog_one2one )
Macaque_ STX5 ( ortholog_one2one )
Mouse_ Stx5a ( ortholog_one2one )
Pig_ STX5 ( ortholog_one2one )
Rat_ Stx5 ( ortholog_one2one )
OhnologsNA
ParalogsSTX2, STX1A, STX4, STX3, STX1B, STX19, STX11, STX17, STX16, STX12, STX7, TSNARE1
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 3EFO  (X-ray  2.70A 
DBSNP rs3802945  rs11231241  rs746774052 
Subcellular location [CC]Endoplasmic reticulum-Golgi intermediate compartment membrane {ECO:0000250|UniProtKB:Q08851};
Single-pass type IV membrane protein {ECO:0000255}. Golgi apparatus membrane {ECO:0000269|PubMed:27795424}. Note=Localizes throughout the Golgi apparatus, but most abundant in the cis-most cisternae. {ECO:0000269|PubMed:27795424}.
Mouse PG classificationNA
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