| Gene Information | |
|---|---|
| Gene Name | AATF |
| Organism | Homo sapiens (Human) |
| Gene Length | 560 |
| Protein Names | Protein AATF (Apoptosis-antagonizing transcription factor) (Rb-binding protein Che-1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000275700 ) 3 ( ENSG00000276072 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9NY61 |
| Gene Card | AATF |
| Uniprot ID | Q9NY61 |
| Pfam | PF13339; PF08164 |
| In ASD | no |
| Allosteric Prediction | no (-0.22870683) |
| Ortholog in Animals | Alpaca_ AATF ( ortholog_one2one ) Dog_ AATF ( ortholog_one2one ) GuineaPig_ AATF ( ortholog_one2one ) Macaque_ AATF ( ortholog_one2one ) Mouse_ Aatf ( ortholog_one2one ) Pig_ AATF ( ortholog_one2one ) Rat_ Aatf ( ortholog_one2one ) Rabbit_ AATF ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. Expressed at high levels in brain, heart, kidney, placenta and thymus. {ECO:0000269|PubMed:10783144, ECO:0000269|PubMed:11027528}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.453953(Rat);0.100584(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5W6A (X-ray 1.74A ) 7MQ8 (EM 3.60A ) 7MQ9 (EM 3.87A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus, nucleolus {ECO:0000269|PubMed:12429849}. |
| Mouse PG classification | NA |
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