Gene Information
Gene NameALDH6A1
OrganismHomo sapiens (Human)
Gene Length535
Protein NamesMethylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial (MMSDH) (Malonate-semialdehyde dehydrogenase [acylating]) (EC 1.2.1.18) (EC 1.2.1.27) (Aldehyde dehydrogenase family 6 member A1)
Target Namemethylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial
Target TypeNA
Gene Age1488 ( ENSG00000119711 )
Evolutionary StageCellular_organisms
AlphaFoldDBQ02252
Gene CardALDH6A1
Uniprot IDQ02252
PfamPF00171
In ASDno
Allosteric Predictionyes (0.295284266)
Ortholog in AnimalsAlpaca_ ALDH6A1 ( ortholog_one2one )
Dog_ ALDH6A1 ( ortholog_one2one )
GuineaPig_ ALDH6A1 ( ortholog_one2one )
Macaque_ ALDH6A1 ( ortholog_one2one )
Mouse_ Aldh6a1 ( ortholog_one2one )
Pig_ ALDH6A1 ( ortholog_one2one )
Rat_ Aldh6a1 ( ortholog_one2one )
Rabbit_ ALDH6A1 ( ortholog_one2one )
OhnologsNA
ParalogsALDH7A1, ALDH1B1, ALDH3A2, ALDH1A1, ALDH3B1, ALDH3B2, ALDH3A1, ALDH2, ALDH9A1, ALDH1A2, ALDH5A1, ALDH1L1, ALDH1A3, ALDH1L2, ALDH8A1, ALDH4A1, ALDH16A1
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.002559(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs72552258 
Subcellular location [CC]Mitochondrion.
Mouse PG classificationNA
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