| Gene Information | |
|---|---|
| Gene Name | KAT6B |
| Organism | Homo sapiens (Human) |
| Gene Length | 2073 |
| Protein Names | Histone acetyltransferase KAT6B (EC 2.3.1.48) (Histone acetyltransferase MOZ2) (MOZ, YBF2/SAS3, SAS2 and TIP60 protein 4) (MYST-4) (Monocytic leukemia zinc finger protein-related factor) |
| Target Name | histone acetyltransferase kat6b |
| Target Type | Literature-reported target |
| Gene Age | 680 ( ENSG00000156650 ) 3 ( ENSG00000281813 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8WYB5 |
| Gene Card | KAT6B |
| Uniprot ID | Q8WYB5 |
| Pfam | PF01853; PF00628; PF17772 |
| In ASD | no |
| Allosteric Prediction | no (-0.222858609) |
| Ortholog in Animals | Alpaca_ KAT6B ( ortholog_one2one ) Dog_ KAT6B ( ortholog_one2one ) GuineaPig_ KAT6B ( ortholog_one2one ) Macaque_ KAT6B ( ortholog_one2one ) Mouse_ Kat6b ( ortholog_one2one ) Pig_ KAT6B ( ortholog_one2one ) Rat_ Kat6b ( ortholog_one2one ) Rabbit_ KAT6B ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | KAT8, KAT6A, PHF10, KAT7, DPF1, DPF3, DPF2, RSF1, KAT5 |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed, with high levels in heart, pancreas, testis and ovary. {ECO:0000269|PubMed:10497217}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);NULL(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 5U2J (X-ray 1.60A ) 6OIE (X-ray 2.08A ) |
| DBSNP | rs57372986 rs3740321 |
| Subcellular location [CC] | Nucleus {ECO:0000305}. |
| Mouse PG classification | LPG |
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