| Gene Information | |
|---|---|
| Gene Name | UTS2R |
| Organism | Homo sapiens (Human) |
| Gene Length | 389 |
| Protein Names | Urotensin-2 receptor (UR-2-R) (G-protein coupled receptor 14) (Urotensin II receptor) (UR-II-R) |
| Target Name | urotensin ii receptor |
| Target Type | Clinical trial target |
| Gene Age | 36 ( ENSG00000181408 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9UKP6 |
| Gene Card | UTS2R |
| Uniprot ID | Q9UKP6 |
| Pfam | PF00001 |
| In ASD | yes |
| Allosteric Prediction | yes (0.955230208) |
| Ortholog in Animals | Alpaca_ UTS2R ( ortholog_one2one ) Macaque_ UTS2R ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | KISS1R, SSTR5, SSTR4, NPBWR1, OPRL1, GPR149, OPRM1, OPRK1, PTGDR2, SSTR3, CMKLR2, SSTR1, LTB4R, LTB4R2, NPBWR2, SSTR2, OPRD1 |
| Tissue | NA |
| Tissue Specificity | Most abundant expression in the heart and pancreas. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6HVK (NMR - ) |
| DBSNP | rs34442190 rs770047242 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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