Gene Information
Gene NameGNRH2
OrganismHomo sapiens (Human)
Gene Length120
Protein NamesProgonadoliberin-2 (Progonadoliberin II) [Cleaved into: Gonadoliberin-2 (Gonadoliberin II) (Gonadotropin-releasing hormone II) (GnRH II) (Luliberin II) (Luteinizing hormone-releasing hormone II) (LH-RH II); GnRH-associated peptide 2 (GnRH-associated peptide II)]
Target NameNA
Target TypeNA
Gene Age86 ( ENSG00000125787 )
Evolutionary StageMammalia
AlphaFoldDBO43555
Gene CardGNRH2
Uniprot IDO43555
PfamPF00446
In ASDno
Allosteric Predictionno (-0.166950387)
Ortholog in AnimalsAlpaca_ GNRH2P ( ortholog_one2one )
Macaque_ GNRH2 ( ortholog_one2one )
Pig_ GNRH2 ( ortholog_one2one )
OhnologsNA
ParalogsGNRH1
TissueNA
Tissue SpecificityMidbrain;
expressed at significantly higher levels outside the brain (up to 30-fold), particularly in the kidney, bone marrow and prostate.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs6051545 
Subcellular location [CC]Secreted.
Mouse PG classificationNA
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